England [ Images ] all rounder Andrew Flintoff [ Images ] has been withdrawn from the one-day international series against South Africa [ Images ] to undergo surgery on a long-standing ankle injury.
The England and Wales Cricket Board replaced him with seamer Matthew Hoggard [ Images ] on Tuesday for the seven-match one-day series starting on Sunday.
"Flintoff will return home tomorrow (Wednesday) to see a specialist to confirm an early date for surgery," England media manager David Clarke told reporters.
"Hoggard will remain on tour to play in the one-day series."
The 27-year-old Flintoff, named by the International Cricket Council [ Images ] as the world's leading one-day player last year, has been plagued by a bone spur in his left ankle for a couple of seasons. He has received cortisone injections to alleviate the problem.
Clarke said fast bowler Simon Jones, who was also not in the original one-day squad, would remain in South Africa as cover for Stephen Harmison, who has an injured left calf.
"We're looking for Jones to play a full part in the one-day squad," Clarke added.
The five-match Test series between South Africa and England was due to end on Tuesday in Centurion, with England 2-1 ahead and on the brink of their first series success in South Africa since 1964-5.
Flintoff has played 40 one-dayers for England and is key to the side's balance. Hoggard has had a superb Test series against South Africa but has not been part of the England one-day set up for two years. He played the last of his 20 one-dayers against Australia [ Images ] in Sydney [ Images ] on January 23, 2003.

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